Patented biomarker for cardiac injury. 

A 0/1h-algorithm using cardiac myosin-binding protein C for early diagnosis of myocardial infarction

Abstract

Aims

Cardiac myosin-binding protein C (cMyC) demonstrated high diagnostic accuracy for the early detection of non-ST-elevation myocardial infarction (NSTEMI). Its dynamic release kinetics may enable a 0/1h-decision algorithm that is even more effective than the ESC hs-cTnT/I 0/1 h rule-in/rule-out algorithm.

Conclusion

The cMyC 0/1h-algorithm provided excellent safety and identified a greater proportion of patients suitable for direct rule-out or rule-in based on a single measurement than the ESC 0/1h-algorithm using hs-cTnT/I.


cMyC reduces the observation group with 18-27% after first blood sample compared with hs-cTn

cMyC observation group reduced after first blood sample compared to hs-cTn
cMyC reduces the observation group with 18-27% after first blood sample compared with hs-cTn
cMyC 0/1h-algorithm for triaging chest pain patients for AMI (Acute Myocardial Infarction)
cMyC 0/1h-algorithm for triaging chest pain patients for AMI (Acute Myocardial Infarction)