Cardiac myosin-binding protein C (cMyC) is a cardiac-specific sarcomeric protein with faster release kinetics compared with those of high-sensitivity cardiac troponin (hs-cTn). CMyC adds significant incremental value to hs-cTn values in the early diagnosis of NSTEMI, improving diagnostic discrimination and enabling more patients to be safely and immediately ruled out for NSTEMI. The single blood draw dual-biomarker strategy is particularly attractive in busy ED settings due to its simplicity and quick time-to-decision.
Incremental Value of cMyC for the Early Diagnosis of AMI
- Pedro Lopez-Ayala, Jasper Boeddinghaus, Luca Koechlin, Paolo Bima, Jonas Glaeser, Carlos C. Spagnuolo, Luca Crisanti, Oscar Miro, Francisco Javier Martín-Sánchez, Michael Christ, Karin Wildi, Simona Piazza, Thomas Nestelberger, Maria Rubini Gimenez, Juliane Gehrke, Jude Formambuh, Emel Kaplan, Gabrielle Hure, Tobias Breidthardt, Evangelos Giannitsis, Bertil Lindahl, Michael Marber, Felix Mahfoud, Ivo Strebel, Christian Mueller
- Incremental Value of Cardiac Myosin-Binding Protein C for the Early Diagnosis of Acute Myocardial Infarction
